The absence of a “head high” would seem to indicate that a suppository does not distribute a systemic dose of cannabis – which corroborates initial research findings about limited bioavailability. The overwhelming majority of patient reports have one thing in common: a lack of intoxication that’s typically caused by smoking or ingesting THC-rich cannabis. Despite the distinct lack of clinical studies, anecdotal accounts from patients are often very positive. Much of the available data pertains to experiments conducted on animals, not on people who actually use suppositories. With contradictory claims from proponents and skeptics regarding the rectal bioavailability of THC, intoxication (or lack thereof), and alleviation of symptoms of difficult-to-treat diseases, it’s time to get a grip on what we really know about this method of administering cannabis.Ĭlinical research on cannabis suppositories is still limited. The back door is making a comeback - medically speaking.Ĭannabis suppositories have grown in popularity, but how and to what extent they actually work remains a mystery. Full Spectrum, Broad Spectrum or Isolate?.
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